Lactobionic acid, also known as galacto-gluconic acid, is an organic acid traditionally produced by chemical oxidation of lactose. Several groups have developed a fermentation route to lactobionic acid from lactose.
The applications in pharmaceuticals, dietary supplements, cosmetics and foods are listed. The production process, including chemical synthesis and microbial fermentation are reviewed. Producers, output and prices of lactobionic acid are given. The projected market by 2020 is assessed.